Oxidative damage to proteins involved in the acrosome reaction, such as acrosin and hyaluronidase, impairs the sperms ability to release these enzymes, preventing successful penetration of the oocyte (79, 80)
(7) Studies have documented enhanced cell division rates in response to IGF-DES compared to equivalent concentrations of native IGF-1
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However, this method is debated as it can cause partial reactions
